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Disodium alpha-ketoglutarate, CAS 305-72-6

Disodium alpha-ketoglutarate, CAS 305-72-6

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Disodium 2-oxoglutarate (also known as disodium alpha-ketoglutarate, disodium oxopetanedioate) is a is an essential Krebs cycle metabolite which participates in a variety of biological processes including anti-oxidative defense, energy production, signaling modules, and genetic engineering. This keto-acid possesses immense commercial value as it is utilized as a precursor to a variety of value-added products such as ethylene and heterocyclic compounds. The 2-oxoglutarate moiety has been suggested to play a role as a signal metabolite in plant cellular metabolic processes. Chemically, ketoglutarate is also a precursor for making glutamate and can be used as an internal standard or biomarker. Functionally, the ketoglutarate moiety is involved in transamination reactions during the metabolism of amino acids where it forms glutamic acid by combining with ammonia and reduces nitrogen by combining with it as well.

  • Tech Specs

    Appearance: colorless to yellowish powder

    Product ID: KGLU1313

    CAS: 305-72-6

    Purity: 98%+

    Formula: C5H4Na2O5

    MW: 192.08g/mol
    MP: 250-253C

    Solubility: water soluble

    SMILES: OC(C([O-])=O)CCC([O-])=O.[Na+].[Na+]

    MDL: MFCD00043347

    HS Code: 291830

    LD50, rat (oral) > 7000mg/kg

  • Synonyms

    sodium 2-hydroxypentanedioate; 2-oxoglutaric acid disodium salt; disodium α-ketoglutarate; 2-oxo-pentanedioic acid, sodium salt (1:2); disodium 2-oxopentanedioate

  • Tags

    metabolite; biomarker; biochemical; keto acid; disodium; dicarboxylate; alpha-ketoglutarate; nitrogen fixer

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